Catalog Number - 62308-05P-4

Hyper Similars C8™ Octyl is a traditional reversed-phase HPLC stationary phase developed for laboratories seeking a high-quality alternative to established C8 methods. As part of the Cogent™ Similars product line, it uses high-purity Type-B spherical silica with a bonded octyl (C8) ligand and endcapping to provide reliable chromatographic performance and excellent method reproducibility. Its surface characteristics are designed to closely match those of legacy Hypersil® and Spherisorb® C8 columns, making it particularly useful for method transfer and replacement applications.

62308-05P-4 is a 50 mm x 4.0 mm ID analytical column packed with 3 µm, 150Å Hyper Similars C8 particles. The short 50 mm length is optimized for fast analyses, rapid equilibration, and reduced solvent consumption while maintaining excellent chromatographic efficiency. The 3 µm particle size provides greater efficiency and sharper peaks than comparable 5 µm columns, although increased operating backpressure should be expected. The 4.0 mm ID format typically operates at approximately 0.8–1.5 mL/min on conventional HPLC systems and is often selected when reproducing legacy methods that specify 4.0 mm ID columns.

This USP L7 column is an excellent alternative for methods developed on Thermo Fisher Hypersil™ C8, Spherisorb®, and similar octyl phases. The C8 chemistry is well suited for hydrophobic and neutral compounds analyzed under reversed-phase conditions and is particularly useful when less retention is desired than with a C18 column. Common applications include long-chain fatty acids, pharmaceutical compounds, and method transfer projects requiring selectivity comparable to traditional C8 stationary phases. This Special Order Item is manufactured upon receipt of order and is subject to Special Order terms.

Key Benefits

• Type-B spherical silica stationary phase

• Suitable alternative for USP L7 methods

• Comparable selectivity to Hypersil® and Spherisorb® C8 columns

• Fast analysis with 50 mm column length

• Higher efficiency with 3 µm particles

• Reduced solvent consumption

• Less retention than C18 columns

• End-capped octyl (C8) bonded phase

Typical Applications

• USP L7 methods

• Reversed-phase HPLC

• Fast analytical methods

• Pharmaceutical analysis

• Quality control testing

• Long-chain fatty acid analysis

• Method transfer and validation

• High-throughput laboratories

Specifications

• Product Type: HPLC Column

• Stationary Phase: Hyper Similars C8 Octyl

• USP Classification: L7

• Particle Size: 3 µm

• Particle Type: Type-B Spherical Silica

• Bonded Phase: C8 (Octyl)

• Endcapped: Yes

• Pore Size: 150Å

• Column Dimensions: 4.0 mm ID x 50 mm

• Length: 50 mm

• Recommended Flow Rate: 0.8–1.5 mL/min

• Brand: Cogent

Special Order Item Information

This item is a Special Order Item manufactured specifically to customer requirements.

• Manufactured upon receipt of order.

• May have extended lead times compared to stocked products.

• Learn more about Special Order Items and policies

Important Notes

• Designed for reversed-phase chromatography

• Short 50 mm length optimized for speed and throughput

• 3 µm particles provide higher efficiency and sharper peaks

• Higher backpressure than comparable 5 µm columns

• Compatible with conventional HPLC systems

• Provides less retention than comparable C18 stationary phases

• Special Order Item

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